- Test Name
- Alpha 1 Antitrypsin
- Aliases
- A1A; A1AT
- Provincial Mnemonic
- A1ATR
- LOINC Test Code
- 1825-9
- Description and Primary Use
- Severe alpha1-antitrypsin deficiency in children most frequently presents as liver disease, cholestasis and cirrhosis. Low levels may be associated with liver cirrhosis, liver tumors and other hepatic and pulmonary problems. Alpha1-antitrypsin deficiency in adults results in pulmomary emphysemia and hepatic diseases. As alpha1-antitrypsin is an acute-phase protein, it's level can increase several fold in acute or active chronic infammation. Therefore, patients with alpha1-antitrypsin deficiency may have falsely normal levels during acute illness.
- Reorder interval
- Not yet defined
- TAT
- ≤3 Days
- Test Cost
- Not Available
- Tier
- 1 - General Availability
- Ordering Requirements (Restrictions / Conditions)
No Restrictions
- Required Consultations
- None
- Algorithms and Guidelines
None
- Special Patient Preparation
None
- Special Collection / Transport / Processing Requirements
No special requirement
- Criteria for Rejection
Based on specimen condition and stability
- Laboratory Service Area
- Clinical Chemistry
- Performing Laboratory / Site
- Category 4 Laboratory (HSC only)
- Last Updated
- 26-Aug-19